The Element 2 High-Resolution ICPMS is from the good ole boys at Thermo, who have now merged with Fisher Scientific to form a massive company that can sell you anything from post it notes to 1-Aryl-2-Pyrrolidinones. With more resolution like this, you might be able to tell the difference between 32S-33S and 65Cu. Did you know that there is a lot of sulfur in seawater, but not a lot of copper? Makes it hard to analyze for copper. Oh ya, mass 63 doesn't work either because of ArNa :)
Showing posts with label research. Show all posts
Showing posts with label research. Show all posts
Thursday, January 04, 2007
Check out Notre Dame's ICPMS lab
This place looks pretty sweet, except for the exhaust tubes hanging all over the place. If they analyze samples for free, can I sub-contract?
The Element 2 High-Resolution ICPMS is from the good ole boys at Thermo, who have now merged with Fisher Scientific to form a massive company that can sell you anything from post it notes to 1-Aryl-2-Pyrrolidinones. With more resolution like this, you might be able to tell the difference between 32S-33S and 65Cu. Did you know that there is a lot of sulfur in seawater, but not a lot of copper? Makes it hard to analyze for copper. Oh ya, mass 63 doesn't work either because of ArNa :)
The Element 2 High-Resolution ICPMS is from the good ole boys at Thermo, who have now merged with Fisher Scientific to form a massive company that can sell you anything from post it notes to 1-Aryl-2-Pyrrolidinones. With more resolution like this, you might be able to tell the difference between 32S-33S and 65Cu. Did you know that there is a lot of sulfur in seawater, but not a lot of copper? Makes it hard to analyze for copper. Oh ya, mass 63 doesn't work either because of ArNa :)
Sunday, November 26, 2006
Search for ICPMS on digg.com yields no results
I searched for "mass spectrometry" on the user powered news site, digg.com, and got no results. First, I checked under the science topic. Oh, wait there are some stories that come up when the whole site is searched.
Fairly interesting stuff, not newsworthy according to the digg community, but I don't think there are many scientist on there.
At Georgia Tech, this is what they call a nanoscale probe, or the Scanning Mass Spectrometry probe (SMS). It seems like what they are trying to do is take some mass spectrums of protiens, metabolites, and peptides without separating them from the cell/tissue. The associate professor responsible for doing this work is Andrei G. Fedorov. His research is pretty hardcore, talking about crazy ideas for ion sources, see project 7.
I think the way it works is the substrate gets a positive charge, the scanning tip has a negative charge. The scanning tip pulls molecules by charge, but also uses something called Taylor electrohydrodynamic focusing of jets to produce charged ions.
Fairly interesting stuff, not newsworthy according to the digg community, but I don't think there are many scientist on there.
At Georgia Tech, this is what they call a nanoscale probe, or the Scanning Mass Spectrometry probe (SMS). It seems like what they are trying to do is take some mass spectrums of protiens, metabolites, and peptides without separating them from the cell/tissue. The associate professor responsible for doing this work is Andrei G. Fedorov. His research is pretty hardcore, talking about crazy ideas for ion sources, see project 7.
I think the way it works is the substrate gets a positive charge, the scanning tip has a negative charge. The scanning tip pulls molecules by charge, but also uses something called Taylor electrohydrodynamic focusing of jets to produce charged ions.
Monday, May 01, 2006
Ophiobolin C
I worked on the synthesis of this molecule while in school at FSU as an undergraduate. It was one of my better academic experiences in Tallahassee. I had my own lab bench, my own glassware, and my own chemicals. I guess it was a taste of graduate school without the 80 hours a week. I met a lot of great people in there; post docs and graduate students who have all dispersed across the world from England to China. When I retire, I'm going to build a
laboratory and make natural products.
Monday, April 24, 2006
DARTs and MS
I'm sure all the mass spec people have heard about this before because it is so cool and also one year old news. It's a new ionization method called DART (direct analysis in real time) invented by Robert B. Cody of JEOL USA and James A. Laramee of EAI Corp. It is a sample introduction system that can be coupled to a mass spectrometer, currently only coupled to a MS by JEOL.
The major difference here, compared to other mass specs, is the sample inlet is at atmospheric pressure. You can hold an object, such as an orange, up in front of the sample cone and get a reading of masses detected and find fungicides.
This technique works by applying an electrical potential to a gas (N2 or H2) to form a plasma that interacts with the sample and the atmosphere.
It took me a minute to picture the instrument layout in my head, I couldn't, so I went to the website. The path of the ion: First, gas is fed in, a plasma is formed, then the instrument opens up to the atmosphere. So, the open region is between the plasma torch and the sample cone. Then, the rest of the mass spec, the one they use happens to be a time-of-flight.
The major difference here, compared to other mass specs, is the sample inlet is at atmospheric pressure. You can hold an object, such as an orange, up in front of the sample cone and get a reading of masses detected and find fungicides.
This technique works by applying an electrical potential to a gas (N2 or H2) to form a plasma that interacts with the sample and the atmosphere.
It took me a minute to picture the instrument layout in my head, I couldn't, so I went to the website. The path of the ion: First, gas is fed in, a plasma is formed, then the instrument opens up to the atmosphere. So, the open region is between the plasma torch and the sample cone. Then, the rest of the mass spec, the one they use happens to be a time-of-flight.
Friday, April 21, 2006
MS at PittCon
Well, I didn't get to go to PittCon, even though it was only a 4 or 5 hour drive from here. And it looks like I missed out on a lot of cool analytical instrumentation as well as possible job leads.
My favorite company Thermo (read with sarcastic tone) introduced a new type of mass spec. In fact, they claim it is "the first totally new mass analyzer to be introduced to the market in more than 20 years." It is called the LTQ Orbitrap mass spectrometer. To read about its initial research, Anal. Chem. 2000, 72, 1156.
Apparently, the orbitrap takes the place of the quadrupole to separate the ions based on m/z. The orbitrap "has ions spinning around a carefully shaped central electrode while shuttling back and forth over its long axis in harmonic motion at frequencies dependent only on their mass-to-charge ratios," says R. Graham Cooks of Purdue University.
More interesting news from PittCon to come.
My favorite company Thermo (read with sarcastic tone) introduced a new type of mass spec. In fact, they claim it is "the first totally new mass analyzer to be introduced to the market in more than 20 years." It is called the LTQ Orbitrap mass spectrometer. To read about its initial research, Anal. Chem. 2000, 72, 1156.
Apparently, the orbitrap takes the place of the quadrupole to separate the ions based on m/z. The orbitrap "has ions spinning around a carefully shaped central electrode while shuttling back and forth over its long axis in harmonic motion at frequencies dependent only on their mass-to-charge ratios," says R. Graham Cooks of Purdue University.
More interesting news from PittCon to come.
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